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The Cell: A Molecular Approach, Seventh Edition. Geoffrey M. Cooper and Robert E. Hausman. Part I. Fundamentals and Foundations. 1. An Overview of Cells and ...
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Part I. Fundamentals and Foundations
1. An Overview of Cells and Cell Research The Origin and Evolution of Cells Cells as Experimental Models Tools of Cell Biology Key Experiment: HeLa Cells Molecular Medicine: Viruses and Cancer 2. Molecules and Membranes The Molecules of Cells Enzymes as Biological Catalysts Cell Membranes Key Experiment: The Folding of Polypeptide Chains Key Experiment: The Structure of Cell Membranes 3. Bioenergetics and Metabolism Metabolic Energy and ATP Electron Transport and Oxidative Phosphorylation Photosynthesis The Biosynthesis of Cell Constituents Key Experiment: The Chemiosmotic Theory Key Experiment: Antimetabolites and Chemotherapy 4. Fundamentals of Molecular Biology Heredity, Genes, and DNA Expression of Genetic Information Recombinant DNA Detection of Nucleic Acids and Proteins Gene Function in Eukaryotes Key Experiment: The DNA Provirus Hypothesis Key Experiment: RNA Interference 5. Genomics, Proteomics, and Systems Biology Genomes and Transcriptomes Proteomics Systems Biology Key Experiment: The Human Genome Molecular Medicine: Malaria and Synthetic Biology **Part II. The Flow of Genetic Information
7. Replication, Maintenance, and Rearrangements of Genomic DNA DNA Replication DNA Repair DNA Rearrangements Molecular Medicine: Colon Cancer and DNA Repair Key Experiment: Rearrangement of Immunoglobulin Genes 8. RNA Synthesis and Processing Transcription in Bacteria Eukaryotic RNA Polymerases and General Transcription Factors Regulation of Transcription in Eukaryotes Chromatin and Epigenetics RNA Processing and Turnover Key Experiment: Isolation of a Eukaryotic Transcription Factor Key Experiment: The Discovery of snRNPs 9. Protein Synthesis, Processing, and Regulation Translation of mRNA Protein Folding and Processing Regulation of Protein Function Protein Degradation Molecular Medicine: Alzheimer’s Disease Key Experiment: The Discovery of Tyrosine Kinases **Part III. Cell Structure and Function