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An in-depth analysis of sudden death in young athletes, including clinical findings, circumstances of death, causes, and the magnitude of the problem. Topics covered include hypertrophic cardiomyopathy, abnormal origin of coronary arteries, and other causes such as marfan syndrome and myocarditis. The document also discusses screening methods and long-term experiences after cardiac surgery.
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Causes of Sudden Death 29 Probable CV Disease 6 5 1 Idiopathic Concentric hypertrophy (no fiber disarray) Hypoplastic coronaries 1 No CV disease 22 Unequivocal CV dis. 2 Ruptured aorta 3 Atherosclero. CA 3 ALCAPA 14 HOCM**
F excluding trauma, cardiac death is the most frequent cause of sports related death. F 5/100,000 have a condition which predisposes them to sudden death. F 1/200,000 athletes per yr have sudden death F ~12 high school ath. die/yr in U.S.
F Annual mortality rate 2-4% F Mechanism probably acute dysrhythmia(v.tach, v.fib., asystole) F Sudden death most common 10-25 yrs. F Peak age is 14 yrs. F Approx. 40% occur during ahtletics F If there is documented v. tach on holter,death rate 8%.
Increased risk of sudden death ass. with: documented v. tach, family hx. of sudden death, young age of onset of symptoms. Sudden death not related to presence or degree of outflow gradient. NO INTERVENTION(SURG,MEDICAL) HAS BEEN SHOWN TO DECREASE RISK OF SUDDEN DEATH.
F Marfan Syndrome: related to aortic rupture. F Myocarditis: may be associated with acute inflammation and chronic multifocal scarring-- arrthymias F Drugs: anabolic steroids predispose to thrombotic MI, CVA, and cardiomyopathy. COCAINE
F Primary dysrhythmias: a. sudden death reported with SVT,long QT, SSS. b. exercise syncope most common presentation.
F SMA 1: history and PE focused hx of syncope, chest pain, or seizures in patient- always ask about sudden death in family members focused PE looking for path. murmur, gallop, or S4, obvious ectopy
F 60% of important CHD: VSD ASD PS PDA CoA
It ain’t over, til it’s over
F Obstructive lesions F Hypertension F Shunts F pulm. artery hypertension/ distortion F valve regurg
F 50 - 85% incidence of bicuspid Ao valve. -- Late developement of stenosis/insuf- ficiency. Associated with calcific changes midlife event -- infective endocarditis F >50% have mitral abnormalities
Associated abnormalities: -- intracranial aneurysms -- late aortic dissection -- intramural coronary artery disease