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JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
BACHELOR OF PHARMACY
COURSE STRUCTURE AND SYLLABUS
Effective from Academic Year 2022-23 Admitted Batch I Year I semester #Applicable ONLY for the students who have studied Mathematics / Physics / Chemistry at HSC and appearing for Remedial Biology (RB) course. $Applicable ONLY for the students who have studied Physics / Chemistry / Botany / Zoology at HSC and appearing for Remedial Mathematics (RM) course. I Year II semester S. No Course Code Subject L T P Credits 1 PS201 Human Anatomy and Physiology II 3 1 - 4 2 PS202 Pharmaceutical Organic Chemistry-I 3 1 - 4 3 BS203 Biochemistry 3 1 - 4 4 BS204 Pathophysiology 3 1 - 4 5 CS205 Computer Applications in Pharmacy 3 - - 3 6 PS206 Human Anatomy and Physiology II lab - - 4 2 7 PS207 Pharmaceutical Organic Chemistry-I Lab - - 4 2 8 BS208 Biochemistry lab - - 4 2 9 CS209 Computer Applications in Pharmacy lab - - 2 1 10 *MC200 NSS - - - - Total 15 4 14 26 II YEAR I SEMESTER
S.
No Course Code Subject L T P Credits 1 PS101 Human Anatomy and Physiology I 3 1 - 4 2 PS102 Pharmaceutical Analysis I 3 1 - 4 3 PS103 Pharmaceutics 3 1 - 4 4 PS104 Pharmaceutical Inorganic Chemistry 3 1 - 4 5 HS105 Communication skills 2 - - 2 6 BS106/BS107 Remedial Biology#^ / Remedial Mathematics$^2 #/3$^ - - 2 #/3$ 7 PS108 Human Anatomy and Physiology-I lab - - 4 2 8 PS109 Pharmaceutical Analysis I lab - - 4 2 9 PS110 Pharmaceutics lab - - 4 2 10 PS111 Pharmaceutical Inorganic Chemistry lab - - 4 2 11 HS112 Communication skills lab - - 2 1 12 BS113 Remedial Biology lab - - 2 1 Total 16/17 4 20 30 #/ S. No Course Code Course Title L T P Credits 1 PS301 Pharmaceutical Organic Chemistry-II 3 1 0 4 2 PS302 Physical Pharmaceutics-I 3 1 0 4 3 BS303 Pharmaceutical Microbiology 3 1 0 4 4 PC304 Pharmaceutical Engineering 3 1 0 4
II YEAR II SEMESTER
S. No Course Code Course Title L T P Credits 1 PS401 Pharmaceutical Organic Chemistry-III 3 1 0 4 2 PC402 Physical Pharmaceutics-II 3 1 0 4 3 PS403 Pharmacology-I 3 1 0 4 4 PC404 Pharmacognosy and Phytochemistry-I 3 1 0 4 5 PS405 Pharmaceutical Jurisprudence 3 1 0 4 6 PC406 Physical Pharmaceutics-II Lab 0 0 4 2 7 PS407 Pharmacology-I Lab 0 0 4 2 8 PC408 Pharmacognosy and Phytochemistry-I Lab 0 0 4 2 9 *MC400 Gender Sensitization Lab 1 0 0 0 Total Credits 16 05 12 26 III Year I Semester S. No. Course Code Course Title L T P Credits 1 PS501 Medicinal Chemistry I 3 1 0 4 2 PS502 Industrial Pharmacy - I 3 1 0 4 3 PS503 Pharmacology II 3 1 0 4 4 PS504 Pharmacognosy and Phytochemistry - II 3 1 0 4 5 PS PS PS PS Open Elective - I I. Generic Product Development II. Green Chemistry III. Cell and Molecular Biology IV. Cosmetic science
6 PC509 Medicinal Chemistry I Lab 0 0 4 2 7 PS510 Industrial Pharmacy – I lab 0 0 4 2 8 PS511 Pharmacology - II lab 0 0 4 2 9 PS512 Pharmacognosy and Phytochemistry - II lab 0 0 4 2 10 *MC500 Environmental sciences 1 0 0 0 Total 16 05 16 28 III Year II Semester S. No. Course Code Course Title L T P Credits 1 PS601 Medicinal Chemistry - II 3 1 0 4 2 PS602 Pharmacology - III 3 1 0 4 3 PS603 Herbal Drug Technology 3 1 0 4 4 PS604 Biopharmaceutics and Pharmacokinetics 3 1 0 4 5 PS PS PS PS Open Elective - II I. Pharmaceutical Quality Assurance II. Pharmaceutical Biotechnology III. Bioinformatics IV. Screening Methods in Pharmacology
6 PS609 Medicinal chemistry - II lab 0 0 4 2 5 PS305 Pharmaceutical Organic Chemistry-II Lab 0 0 4 2 6 PS306 Physical Pharmaceutics-I Lab 0 0 4 2 7 BS307 Pharmaceutical Microbiology Lab 0 0 4 2 8 PC308 Pharmaceutical Engineering Lab 0 0 4 2 10 *MC300 NSO 0 0 0 0 Total Credits 12 04 16 24
PS101: HUMAN ANATOMY AND PHYSIOLOGY - I
B. Pharm. I Year I Sem L T P C 3 1 0 4 Scope: This subject is designed to impart fundamental knowledge on the structure and functions of the various systems of the human body. It also helps in understanding both homeostatic mechanisms. The subject provides the basic knowledge required to understand the various disciplines of pharmacy. Course Objectives: Upon completion of this course the student should be able to Explain the gross morphology, structure, and functions of various organs of the human body. Describe the various homeostatic mechanisms and their imbalances. Identify the various tissues and organs of different systems of human body. Perform the various experiments related to special senses and nervous system. Appreciate coordinated working pattern of different organs of each system UNIT –I 10 hours Introduction to human body Definition and scope of anatomy and physiology, levels of structural organization and body systems, basic life processes, homeostasis, basic anatomical terminology. Cellular level of organization Structure and functions of cell, transport across cell membrane, cell division, cell junctions. General principles of cell communication, intracellular signaling pathway activation by extracellular signal molecule, Forms of intracellular signaling: a) Contact-dependent b) Paracrine c) Synaptic d) Endocrine Tissue level of organization Classification of tissues, structure, location and functions of epithelial, muscular and nervous and connective tissues. UNIT – II 10 hours Integumentary system Structure and functions of skin Skeletal system Divisions of skeletal system, types of bone, salient features, and functions of bones of axial and appendicular skeletal system Organization of skeletal muscle, physiology of muscle contraction, neuromuscular junction Joints Structural and functional classification, types of joints movements and its articulation UNIT – III 10 hours Nervous system Organization of nervous system, neuron, neuroglia, classification and properties of nerve fibre, electrophysiology, action potential, nerve impulse, receptors, synapse, neurotransmitters. Central nervous system: Meninges, ventricles of brain and cerebrospinal fluid. Structure and functions of brain (cerebrum, brain stem, cerebellum), spinal cord (gross structure, functions of afferent and efferent nerve tracts, reflex activity) UNIT – IV 08 hours Peripheral nervous system: Classification of peripheral nervous system: Structure and functions of sympathetic and parasympathetic nervous system. Origin and functions of spinal and cranial nerves. Special senses: Structure and functions of eye, ear, nose and tongue and their disorders.
UNIT – V 07 hours Endocrine system Classification of hormones, mechanism of hormone action, structure and functions of pituitary gland, thyroid gland, parathyroid gland, adrenal gland, pancreas, pineal gland, thymus and their disorders. TEXT BOOKS: (Latest Editions)
- Essentials of Medical Physiology by K. Sembulingam and P. Sembulingam. Jaypeebrothers medical publishers, New Delhi.
- Anatomy and Physiology in Health and Illness by Kathleen J.W. Wilson, Churchill Livingstone, New York
- Physiological basis of Medical Practice-Best and Tailor. Williams & Wilkins Co, Riverview, MI USA
- Text book of Medical Physiology- Arthur C, Guyton and John.E. Hall. Miamisburg, OH, U.S.A.
- Principles of Anatomy and Physiology by Tortora Grabowski. Palmetto, GA, U.S.A.
- Textbook of Human Histology by Inderbir Singh, Jaypee brother’s medical publishers, New Delhi.
- Textbook of Practical Physiology by C.L. Ghai, Jaypee brother’s medical publishers, New Delhi.
- Practical workbook of Human Physiology by K. Srinageswari and Rajeev Sharma, Jaypee brother’s medical publishers, New Delhi. REFERENCE BOOKS: (Latest Editions)
- Physiological basis of Medical Practice-Best and Tailor. Williams & Wilkins Co, Riverview, MI USA
- Text book of Medical Physiology- Arthur C, Guyton and John. E. Hall. Miamisburg, OH, U.S.A.
- Human Physiology (vol 1 and 2) by Dr. C.C. Chatterrje, Academic Publishers Kolkata
TEXT BOOKS: (Latest Editions)
- A.H. Beckett & J.B. Stenlake's, Practical Pharmaceutical Chemistry Vol I & II, Stahlone Press of University of London
- Introduction to Pharmaceutical Analysis by Badwaik Hemant R. published by Pharma Med Press
- A.I. Vogel, Text Book of Quantitative Inorganic analysis
- P. Gundu Rao, Inorganic Pharmaceutical Chemistry
- Bentley and Driver's Textbook of Pharmaceutical Chemistry
- John H. Kennedy, Analytical chemistry principles
- Indian Pharmacopoeia.
- Badwaik Hemant R., Introduction to Pharmaceutical Analysis, Pharma Med Press
PS103: PHARMACEUTICS
B. Pharm. I Year I Sem L T P C 3 1 0 4 Scope: This course is designed to impart a fundamental knowledge on the preparatory pharmacy with arts and science of preparing the different conventional dosage forms. Course Objectives: Upon completion of this course the student should be able to: Know the history of profession of pharmacy Understand the basics of different dosage forms, pharmaceutical incompatibilities and pharmaceutical calculations Understand the professional way of handling the prescription Preparation of various conventional dosage forms UNIT – I 10 Hours Historical background and development of profession of pharmacy: History of profession of Pharmacy in India in relation to pharmacy education, industry, and organization, Pharmacy as a career, Pharmacopoeias: Introduction to IP, BP, USP and Extra Pharmacopoeia. Dosage forms: Introduction to dosage forms, classification and definitions Prescription: Definition, Parts of prescription, handling of Prescription and Errors in prescription. Posology: Definition, Factors affecting posology. Pediatric dose calculations based on age, body weight and body surface area. UNIT – II 10 Hours Pharmaceutical calculations: Weights and measures–Imperial & Metric system, Calculations involving percentage solutions, alligation, proof spirit and isotonic solutions based on freezing point and molecular weight. Powders: Definition, classification, advantages and disadvantages, Simple & compound powders – official preparations, dusting powders, effervescent, efflorescent and hygroscopic powders, eutectic mixtures. Geometric dilutions. Liquid dosage forms: Advantages and disadvantages of liquid dosage forms. Excipients used in formulation of liquid dosage forms. Solubility enhancement techniques UNIT – III 08 Hours Monophasic liquids: Definitions and preparations of Gargles, Mouthwashes, Throat Paint, Eardrops, Nasal drops, Enemas, Syrups, Elixirs, Liniments and Lotions. Biphasic liquids: Suspensions: Definition, advantages and disadvantages, classifications, Preparation of suspensions; Flocculated and Deflocculated suspension & stability problems and methods to overcome. Emulsions: Definition, classification, emulsifying agent, test for the identification of type of Emulsion, Methods of preparation & stability problems and methods to overcome. UNIT – IV 08 Hours Suppositories: Definition, types, advantages and disadvantages, types of bases, methods of preparations. Displacement value & its calculations, evaluation of suppositories. Pharmaceutical incompatibilities: Definition, classification, physical, chemical and therapeutic incompatibilities with examples. UNIV – V 07 Hours Semisolid dosage forms: Definitions, classification, mechanisms and factors influencing dermal penetration of drugs. Preparation of ointments, pastes, creams and gels. Excipients used in semi solid dosage forms. Evaluation of semi solid dosages forms
PS104: PHARMACEUTICAL INORGANIC CHEMISTRY
B. Pharm. I Year I Sem L T P C 3 1 0 4 Scope: This subject deals with the monographs of inorganic drugs and pharmaceuticals. Course Objectives: Upon completion of course, student shall be able to know the sources of impurities and methods to determine the impurities in inorganic drugs and pharmaceuticals understand the medicinal and pharmaceutical importance of inorganic compounds UNIT – I 10 Hours Impurities in pharmaceutical substances: History of Pharmacopoeia, Sources and types of impurities, principle involved in the limit test for Chloride, Sulphate, Iron, Arsenic, Lead and Heavy metals, modified limit test for Chloride and Sulphate General methods of preparation, assay for the compounds superscripted with asterisk (), properties and medicinal uses of inorganic compounds belonging to the following classes UNIT – II 10 Hours Acids, Bases and Buffers: Buffer equations and buffer capacity in general, buffers in pharmaceutical systems, preparation, stability, buffered isotonic solutions, measurements of tonicity, calculations and methods of adjusting isotonicity. Major extra and intracellular electrolytes: Functions of major Physiological ions, Electrolytes used in the replacement therapy: Sodium chloride, Potassium chloride, Calcium gluconate* and Oral Rehydration Salt (ORS), Physiological acid base balance. Dental products: Dentifrices, role of fluoride in the treatment of dental caries, Desensitizing agents, Calcium carbonate, Sodium fluoride, and Zinc eugenol cement. UNIT – III 10 Hours Gastrointestinal agents Acidifiers: Ammonium chloride* and Dil. HCl Antacid: Ideal properties of antacids, combinations of antacids, Sodium Bicarbonate, Aluminum hydroxide gel, Magnesium hydroxide mixture Cathartics: Magnesium sulphate, Sodium orthophosphate, Kaolin and Bentonite Antimicrobials: Mechanism, classification, Potassium permanganate, Boric acid, Hydrogen peroxide, Chlorinated lime, Iodine and its preparations UNIT – IV 08 Hours Miscellaneous compounds Expectorants: Potassium iodide, Ammonium chloride. Emetics: Copper sulphate, Sodium potassium tartarate Haematinics: Ferrous sulphate, Ferrous gluconate Poison and Antidote: Sodium thiosulphate*, Activated charcoal, Sodiumnitrite Astringents: Zinc Sulphate, Potash Alum UNIT – V 07 Hours Radiopharmaceuticals: Radio activity, Measurement of radioactivity, Properties of á, â, ã radiations, Half life, radio isotopes and study of radio isotopes - Sodium iodide I^131 , Storage conditions, precautions & pharmaceutical application of radioactive substances.
TEXT BOOKS: (Latest Editions)
- A.H. Beckett & J.B. Stenlake's, Practical Pharmaceutical Chemistry Vol I & II, Stahlone Press of University of London, 4th^ edition.
- A.I. Vogel, Text Book of Quantitative Inorganic analysis
- P. GunduRao, Inorganic Pharmaceutical Chemistry, 3rd^ Edition
- M.L Schroff, Inorganic Pharmaceutical Chemistry
- Bentley and Driver's Textbook of Pharmaceutical Chemistry
- Anand&Chatwal, Inorganic Pharmaceutical Chemistry
- IndianPharmacopoeia
- Algarsamy V. Pharmaceutical Inorganic Chemistry, 2nd Ed. Pharma Med Press
- Rao Somasekhar, Pharmaceutical Inorganic Chemistry, Pharma Med Press
Group Discussion: Introduction, Communication skills in group discussion, Do’s and Dont’s of group discussion TEXT BOOKS: (Latest Editions)
- Basic communication skills for Technology, Andreja. J. Ruther Ford, 2nd^ Edition, Pearson Education, 2011
- Communication skills, Sanjay Kumar, Pushpalata, 1st^ Edition, Oxford Press, 2011
- Organizational Behaviour, Stephen. P. Robbins, 1st^ Edition, Pearson, 2013
- Brilliant- Communication skills, Gill Hasson, 1st^ Edition, Pearson Life, 2011
- The Ace of Soft Skills: Attitude, Communication and Etiquette for success, GopalaSwamy Ramesh, 5th^ Edition, Pearson, 2013
- Developing your influencing skills, Deborah Dalley, Lois Burton, Margaret, Green Hall, 1st Edition Universe of Learning LTD, 2010
- Communication skills for professionals, Konarnira, 2nd^ Edition, New arrivals – PHI, 2011
- Personality development and soft skills, Barun K Mitra, 1st Edition, Oxford Press, 2011
- Soft skill for everyone, Butter Field, 1st Edition, Cengage Learning India pvt. ltd, 2011
- Soft skills and professional communication, Francis Peters SJ, 1 st^ Edition, McGraw Hill Education, 2011
- Effective communication, John Adair, 4th^ Edition, Pan Mac Millan, 2009
- Bringing out the best in people, Aubrey Daniels, 2nd^ Edition, McGraw Hill, 1999
- Rao Bhaskara, Communication Skills, BS Publications
BS106: REMEDIAL BIOLOGY
B. Pharm. I Year I Sem L T P C 2 0 0 2 Scope: To learn and understand the components of living world, structure and functional system of plant and animal kingdom. Course Objectives: Upon completion of the course, the student shall be able to know the classification and salient features of five kingdoms of life understand the basic components of anatomy & physiology of plant know understand the basic components of anatomy & physiology animal with special reference to human UNIT - I 07 Hours Living world: Definition and characters of living organisms Diversity in the living world Binomial nomenclature Five kingdoms of life and basis of classification. Salient features of Monera, Potista, Fungi, Animalia and Plantae, Virus, Morphology of Flowering plants Morphology of different parts of flowering plants – Root, stem, inflorescence, flower, leaf, fruit, seed. General Anatomy of Root, stem, leaf of monocotyledons &Dicotylidones. UNIT – II 07 Hours Body fluids and circulation Composition of blood, blood groups, coagulation of blood, Composition and functions of lymph Human circulatory system, Structure of human heart and blood vessels, Cardiac cycle, cardiac output and ECG Digestion and Absorption Human alimentary canal and digestive glands, Role of digestive enzymes, Digestion, absorption and assimilation of digested food Breathing and respiration Human respiratory system, Mechanism of breathing and its regulation, Exchange of gases, transport of gases and regulation of respiration, Respiratory volumes UNIT – III 07 Hours Excretory products and their elimination Modes of excretion, Human excretory system- structure and function, Urine formation, Rennin angiotensin system Neural control and coordination Definition and classification of nervous system, Structure of a neuron, Generation, and conduction of nerve impulse, Structure of brain and spinal cord, Functions of cerebrum, cerebellum, hypothalamus, and medulla oblongata Chemical coordination and regulation Endocrine glands and their secretions, Functions of hormones secreted by endocrine glands Human reproduction Parts of female reproductive system, Parts of male reproductive system, Spermatogenesis and Oogenesis, Menstrual cycle UNIT – IV 05 Hours Plants and mineral nutrition:
BS107: REMEDIAL MATHEMATICS
B. Pharm. I Year I Sem L T P C 3 0 0 3 Scope: This is an introductory course in mathematics. This subject deals with the introduction to Partial fraction, Logarithm, matrices and Determinant, Analytical geometry, Calculus, differential equation and Laplace transform. Course Objectives: Upon completion of the course the student shall be able to:- Know the theory and their application in Pharmacy Solve the different types of problems by applying theory Appreciate the important application of mathematics in Pharmacy UNIT – I 06 Hours Matrices and Determinant: Introduction matrices, Types of matrices, Operation on matrices, Transpose of a matrix, Matrix Multiplication, Determinants, Properties of determinants, Product of determinants, Singular and non- singular matrices, Inverse of a matrix, Solution of system of linear of equations using Gauss Elimination method. UNIT- II 06 Hours Logarithms: Introduction, Definition, Theorems/Properties of logarithms, Common logarithms, Characteristic and Mantissa, worked examples, application of logarithm to solve pharmaceutical problems. Function: Real Valued function, Classification of real valued functions UNIT – III 06 Hours Calculus Limits and continuity: Introduction, Limit of a function, Definition of limit of a function Differentiation: Introductions, properties of derivatives, Finding derivative of a function usinf Standard Derivatives, Derivative of the sum or difference of two functions, Derivative of the product of two functions (product formula), Derivative of the quotient of two functions (Quotient formula) – Without Proof. Related problem. UNIT – IV 06 Hours Integration: Introduction, Definition, Standard formulae, Rules of integration, Method of substitution, Method of Partial fractions, Integration by parts, definite integrals, application UNIT – V 06 Hours Differential Equations: Some basic definitions, Order and degree, Equations in separable form, Homogeneous equations, Linear Differential equations, Exact equations, Application in solving Pharmacokinetic equations TEXT BOOKS: (Latest Edition)
- Differential Calculus by Shanthinarayan
- Intermediate telugu academy mathematics text book
- Integral Calculus by Shanthinarayan
- Higher Engineering Mathematics by Dr.B.S. Grewal
- A Text Book of Remedial Mathematics by P seshagiri Rao, Pharmamed Press.
PS108: HUMAN ANATOMY AND PHYSIOLOGY- I Lab B. Pharm. I Year I Sem L T P C 0 0 4 2 Practical physiology is complimentary to the theoretical discussions in physiology. Practicals allow the verification of physiological processes discussed in theory classes through experiments on living tissue, intact animals, or normal human beings. This is helpful for developing an insight on the subject. List of Experiments:
- Study of compound microscope.
- Microscopic study of epithelial and connective tissue
- Microscopic study of muscular and nervous tissue
- Identification of axial bones
- Identification of appendicular bones
- To study the integumentary and special senses using specimen, models, etc.,
- To study the nervous system using specimen, models, etc.,
- To study the endocrine system using specimen, models, etc
- To demonstrate the general neurological examination
- To demonstrate the function of olfactory nerve
- To examine the different types of taste.
- To demonstrate the visual acuity
- To demonstrate the reflex activity
- Recording of body temperature
- To demonstrate positive and negative feedback mechanism.
PS110: PHARMACEUTICS LAB
B. Pharm. I Year I Sem L T P C 0 0 4 2 List of Experiments:
- Syrups a) Syrup IP b) Paracetamol pediatric syrup
- Elixirs a) Piperazine citrate elixir b) Paracetamol pediatric elixir
- Linctus a) Simple Linctus BPC
- Solutions a) Strong solution of ammonium acetate b) Cresol with soap solution
- Suspensions a) Calamine lotion b) Magnesium Hydroxide mixture
- Emulsions a) Turpentine Liniment b) Liquid paraffin emulsion
- Powders and Granules a) ORS powder (WHO) b) Effervescent granules c) Dusting powder
- Suppositories a) Glycero gelatin suppository b) Soap glycerin suppository
- Semisolids a) Sulphur ointment b) Non-staining iodine ointment with methyl salicylate c) Bentonite gel
- Gargles and Mouthwashes a) Potassium chlorate gargle b) Chlorhexidine mouthwash REFERENCES BOOKS:
- Pharmaceutics-I (General Pharmacy) A Practical Manual by Mishra Vijay, Pharmamed Press
- Pharmaceutics: A Practical Manual for B PHARM & PHARM D Courses, Abraham Sindhu by Pharmamed Press.
PS111: PHARMACEUTICAL INORGANIC CHEMISTRY - LAB
B. Pharm. I Year I Sem L T P C 0 0 4 2 Limit tests for following ions a) Limit test for Chlorides and Sulphates Modified limit test for Chlorides and Sulphates Limit test for Iron b) Limit test for Heavy metals Limit test for Lead c) Limit test for Arsenic Identification test Magnesium hydroxide Ferrous sulphate Sodium bicarbonate Calcium gluconate Copper sulphate Test for purity a) Swelling power of Bentonite b) Neutralizing capacity of aluminum hydroxide gel c) Determination of potassium iodate and iodine in potassium Iodide Preparation of inorganic pharmaceuticals a) Boric acid b) Potash alum c) Ferrous sulphate REFERENCE BOOK:
- Practical Pharmaceutical In-Organic Chemistry, by Bayya Subba Rao, Pharmamed Press.
