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A detailed overview of the regulation of leukopoiesis, focusing on the key roles of cytokines, particularly colony stimulating factors (csfs), interleukins (ils), and tumor necrosis factors (tnf). It explores the sources, functions, and mechanisms of action of these cytokines in the development, differentiation, and activation of various leukocyte populations. The document also highlights the specific roles of different interleukins, such as il-1, il-2, il-3, il-4, il-5, and il-6, in immune cell maturation and function. Additionally, it delves into the characteristics and functions of gm-csf, g-csf, and m-csf, emphasizing their importance in granulocyte and monocyte development. Finally, the document discusses the role of tnf in inflammation and immune regulation, including its types, sources, functions, and receptor interactions.
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~NAME :AVIGHNA MISHRA ROLL NO.:
INTERLEUKIN- (IL-1) Activated macrophages INTERLEUKIN- (IL-2) T lymphocyte INTERLEUKIN- (IL-3) T lymphocyte INTERLEUKINS- (IL-4) Human mast cells, T cells INTERLEUKIN- (IL-5) Human mast cell, T cells INTERLEUKIN- (IL-6) T lymphocyte, monocyte/ macrophages, fibroblast
G-CSF: