SCIT
:
Weekly
at
first
then
monthly
Bager
et
al
-
SLIT
:
usually
once
daily
LIMITATIONS
:
Large
national
cohort
study
cohort
study
lacked
conducted
in
Denmark
,
long-term
Is
↓
randomisation
yes
study
to
assess
the
long-term
impact
confounding
(for
eg
.
diff
in
adherence
,
selection
baseline
severity
,
of
SCIT
+
SLIT
.
Studies
showed
reduced
bias
or
lifestyle
choices
el
need
for
anti-allergic
medication
during
45
%
uS35
%
between
groups
treatment
,
but
benefits
were
not
sustained
passed
SCIT
SLIT
5
years
.
I
included
this
to
showcase
real
world
and
long
term
data
,
and
other
articles
didn't
do
long-term
Wahn
et
al
.
Limitation
:
real-world
Observational
study
.
So
there's
no
random
allocation
=
selection
bias
possible
Real-world
Cohort
study
Also
outcomes
were
self
reported
-
potential
recall
bias
-
-
65
.
4
%
of
patients
Focused
on
birch
pollen
immunotherapy
using
AIT
were
no
using
SCIT
,
it
showed
reduced
symptoms
,
medication
longer
Using
SAR
reliance
,
and
even
a
reduced
risk
of
developing
asthma
symptomatic
meds
.
over
six
years
·
ind
to
show
SCIT's
long-term
clinical
benefits
49
.
1
%
were
not
using
asthma
meds
up
to
6
yrs
scadding
et
al
.
(2017)
after
stopping
treatment
Randomised
Controlled
trial
(RCT)
was
a
GRAsstrial
,
examined
whether
two
years
of
limitation
:
SLIT
for
grass
pollen
led
to
lasting
symptom
control
.
variable
study
designs
Y
Followed
up
at
three
years
,
study
found
continued
↓
cohort
or
improvement
in
nasal
response
.
Showed
SCIT's
long-term
RCT
Observational
potential
and
was
methodologically
strong
Designs
were
so
studies
different
-
hard
to
draw
one
conclusion
