Organic Compounds Guide: Alkanes, Alcohols, Aldehydes, Ketones, Acids, Amines, Phenols | Summaries Pharmacognosy

· The content of this book is innovative and presented in 31 chapters with simple and uniform pattern of explanation

along with all chemical reactions.

· The book has covered the entire Pharmaceutical organic chemistry, starts from origin of organic chemistry to

Heterocyclic chemistry and Stereochemistry.

· The principles of Organic Chemistry, which is difficult to remember by the students is described in a student friendly

manner and shall be reproduced well in examinations.

· To make the learning comfortable and magnetize the attention we have used color in equations and diagrams.

Salient Features:

· In each chapter, a brief Introduction of the individual chapter, Importance, Detailed discussion of the Basic Theory,

Preparations, Reactions, Test for identification and Applications of each class of compounds in Pharmacy are

described which reflects the title of the book “Pharmaceutical Organic Chemistry”.

· To inspire the readers, Interesting facts about great scientists and organic compounds and their discovery are

given under each chapter.

· As per PCI Revised syllabus the coverage is complete with the basics as well as B. Pharm. 2nd, 3rd and 4th

Semesters portion.

Pharmaceutical Organic Chemistry is a much awaited great work in the field of Chemistry and Pharmacy.

Targeted mainly to B. Pharmacy students, this book will also be useful for Pharm-D, M. Pharmacy, B.Sc. as well as M.Sc.

chemistry and pharmaceutical chemistry students. The main objective of this book is to attract the undergraduate

Pharmacy students and make them to understand the basic principles of Organic Chemistry which can be applied in

Pharmaceutical Chemistry and Medicinal Chemistry. Thus the book is aimed to eliminate the inadequacy in teaching and

learning of Organic Chemistry by providing detailed information about the Organic compounds.

About the Author

Dr. V. Alagarsamy, M. Pharm., PhD, FIC, DOMH, is Professor and Principal of MNR College of

Pharmacy, Sangareddy, Gr. Hyderabad. He received his D.Pharm., from Coimbatore Medical

College, B.Pharm., degree from Madurai Medical College, M.Pharm., from LM College of

Pharmacy, Ahmedabad, PhD from The MS University of Baroda. He has been teaching

Pharmaceutical Organic Chemistry, Pharmaceutical Inorganic Chemistry, Chemistry of Natural

Products and Medicinal Chemistry and performing research work in synthetic medicinal chemistry

on novel heterocyclic bio-active compounds for two decades. For his research work, he has

collaborated with various research laboratories/organizations like National Cancer Institute, USA;

Rega Institute for Medical Research, Belgium; Southern Research Institute, USA; and Sudbury Regional Hospital, Ontario,

Canada. He is a recipient of young scientist award from the Department of Science and Technology, New Delhi. He is the

author/coauthor of over 160 papers, which includes the original research articles and presentations in various conferences

and symposiums. He has also patented his Research findings. He become the co-editor of the International journal

“Antiinfective Agents”, published by Bentham Science Publishers. His Books on the title of “Text Book of Medicinal

Chemistry,” “Pharmaceutical Chemistry of Natural Products,” “Pharmaceutical Inorganic Chemistry,” “Organic

Chemistry - A Comprehensive Approach”and “Practical Pharmaceutical Inorganic Chemistry” are well appreciated in

the academic community. His research activities are supported by the funding agencies like CSIR, DST and DSIR. Dr. V.

Alagarsamy is a member of All India Board of Pharmaceutical Education (AIB-PE), AICTE, New Delhi and a member of

board of studies (Pharmacy) in Osmania University, Hyderabad and is a doctoral committee member and a recognized

research guide for PhD scholars in various universities.

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Organic Compounds Guide: Alkanes, Alcohols, Aldehydes, Ketones, Acids, Amines, Phenols, Summaries of Pharmacognosy

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Pharmaceutical

Organic Chemistry

ISBN: 978-93-89354-77-

PharmaMed Press

My First & Best Teacher - Beloved Mother

Gave me not only Respiration but also Inspiration

Shrimathi. V. KAMUTHAI

The inspirational words of my mother ringing in my ears are…….

As the students entering graduate course, understanding of Pharmaceutical organic chemistry is always

been a difficult task especially the various chemical reactions with their mechanisms of different kind of

organic compounds. Hence my efforts have been devoted to authoring a book by equipping with the

challenging requirements of the subject for the new generations of the teachers all over India and is easy to

read for students who are not necessarily of Pharmacy program, but mainly for the students of first time

reading organic reactions, their mechanisms and their applications in science, Pharmacy and medicine.

Methodical description of each chapter, enriching chemical and pharmaceutical background of the

medicinally important organic compounds, proceeding each group of organic compounds in a systematic

way in easy-to-understand style in the larger interest of the students without any difficulty and making the

reader acquainted thoroughly with chemistry of organic compounds is the unique feature of this book.

In preparing this text book, I have tried to enrich the importance of organic compounds in medicine and

pharmacy, so that the anticipated audience of this book will feel the importance of organic compounds

and made the book a comprehensive. The students of Pharmacy graduates of our country faced with the

scarcity of books to serve their needs. Few of the authors dealt well about the basics of organic chemistry,

but the reactions of organic compounds are not presented in a easy to understand manner which students

felt difficult to learn. Some of the books of organic chemistry fail to give the chemical structures for all

reactions, hence the students are unable to understand the reactions clearly. Hence the content of this

book is made as a humble attempt to cater the needs of academicians belonging to all Indian Universities by

incorporating the chemical structure of all reactions and enriching basic principles of each organic class of

compounds.

The book has covered the entire Pharmaceutical organic chemistry, starting from origin of organic

chemistry to advanced topics like stereochemistry and heterocyclic compounds and it is divided into 31

chapters. Chapter 1 to 7 deals with the basics of the organic chemistry, wherein the fundamentals like

origin and development of organic chemistry, structure of organic molecules and their related properties

are described. Classification and nomenclature of organic compounds and general terms used are also

presented in a systematic way, which is easy to understood and able to reproduce well in examinations.

Chapter 8 to 25 deals with Aliphatic and Aromatic compounds which are further divided into different

chapters and each chapter is dealt with Introduction, Importance of each class of compounds, Nomenclature,

General methods of preparation, General physical and chemical properties and Pharmaceutically important

organic compounds of each chapter are described in a easy to understand manner. Summary of methods

of preparation and chemical reactions in a flow chart manner presented is unique and helps student to

remember for exam which is the first of its kind.

Chapter 26 to 28 , Isomerism and detailed description of optical and geometrical isomerism is presented

in a simplified manner.

Chapter 29 to 30, Heterocyclic rings of various types and their utility in pharmaceutical chemistry is

described well. The medicinal compounds derived from each heterocycles also exemplified which makes

the reader inspiring.

In Chapter 31, Important reactions and reagents used in organic chemistry and some of the special

reactions are described with their mechanism and applications in Pharmaceutical organic chemistry.

To inspire the readers and make them attracted, interesting facts about great scientists and Organic

compounds and their discovery etc are given under each chapters.

In order to help students to remember well and reproduce well in exams, the style and presentation are

followed simple and similar pattern in all chapters. We have also used some special abbreviations like

“CAD” (which helps to remember cold Alkaline dilute).

To help the students to learn and magnetize the attention we have used color in equations and diagrams.

We have done it this thoughtfully and purposefully and not just to make the book attractive. These small

inputs helps a lot for the fresher’s who enter into degree program.

We hope that this special volume will be a good source of information and reference for not only to

graduates and post-graduate students but also for basic and applied researchers in this field. Moreover it

will also be of interest to a wide range of scientists who are involving in the Pharmaceutical organic

chemistry related research. I welcome suggestions and constructive criticism from all corners of scientific

community.

V. Alagarsamy

drvalagarsamy@gmail.com

What is the best way to study organic chemistry?

Preface (vii)

3. Structure of Organic Molecules and

5. Factors Influencing a Chemical Reaction or

7. General Terms used in Organic

31. Reactions and Reagents of

IntroductionIntroductionIntroductionIntroductionIntroduction

IUPIUPIUPIUPIUPAAAAAC System of NomenclatureC System of NomenclatureC System of NomenclatureC System of NomenclatureC System of Nomenclature