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PHARMACEUTICAL GASTROINTESTINAL AGENTS, Study notes of Inorganic Chemistry

Comprehensive notes covering the gastrointestinal tract, related diseases, and therapeutic agents. Includes detailed insights on acidifiers, antacids, cathartics, and antimicrobial agents with ideal properties, classifications, and examples—perfect for pharmacy and medical students seeking clear, concise, and exam-focused material.

Typology: Study notes

2023/2024

Available from 04/18/2025

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Tnorganrc CHEMISTRY GpasTROINTESTINAL A HENTS — The qaatdotnbab nad tant OL olsen tine track oto Adfeud a4 th GI tract or Hx alimentey Karol. > 9t us iwhetant Ayer of cur body: urhich comint Gf ral Cavtly , pharynx, 0 t40 phagua , Atomacs » Amel PtesHre Avo anol Comal. — The win m of OT track lu te olfak onal ab- Bole wucksients {rem trod and to exute Waste prdduets y olfg alien . Gastro inkestnal Agents : the arc th aude or clang ushich Orr used to tact qastao fre thal Cliuorden or chiro - JE Twolwy Various Trongarte anol oper’ c olay - €4-, Acidifias, Prtacidd ; Solitt Cotharticn , & Ark mi vobial Ag pnki . . Aczotrregs — These aur the lings Gr 24 enh that cur Usel te duerase the metabolic acfcoata fe. bo imersme Hue Aeiohity On paste aciol 7, GI tAact. Page> 4 — There agents ae bet worle boo Ways , et ther decusrsiy He bl Oe be Ee aeptig| ae eet 4 oad C by pAcduetng Ht) — > These arr wed dn the tautmat oy Achlar hy dain ow Hypo chlor badhia « T dent bso pertiva 4 Acidttiag © These Ahowsl be hen- Anu beh tb the OT that and dof. for Levy term OL Atfrert We: @ Thay hwat Almain Chive’ colby A table ola ng Atozpe an Oe Mack olmnredy wih, other Prgrdd ends Pn Ha formula- mm. ® Thay Ahold het prMaduce Unfolearant tut or odour tt wight Aiduce palert Complianer. ® They Alveoura| ffich edt Agwser gastaic pi bo aid U4qyhion, OW WebAoue He absotphion of Celalin drags. @ the aciclifi Ahold Occur qi ad tis tiation to Prowat Hime Adid or On Pe Clawidt cabin : ® Gastric acidifiers—> The arr tHe abuys whol ari urea! to Intusre the acidity 6 Hx stormed Py Potters Aettadey from Achlorhydria ov Uypochlorhgaltis See Pedi ie Usaustity 4 HUL aud iy gaat are PAGE 2. ® It alo papa by panrifying He Amel product by Apblwodion or bay bet bing ry bein (ont aati Achim Ltt Agdinn choise Tn eynivalat proportions. PAs uses © dt UA vite » fiw oO COM CA Fen bowder . @® It ws Ahighty Aygioacabic , odours Phoaganic salt tatty a Cooling Alene High . ® I w pay Apluble th water onal 4 ceri ne but Atronyly Aguble fn alestet. Aanoy —> Gta Ana us Carri eal by avid - bare Litrstim. —> Didseoe Lge YF ammchiun, chdartcl, fy WO mL YF Hatilles water. > hdd ao minh A Smt of purtAstises fort olehyole AA. Gm LO wh of HSbiled water: = Tithe ut rot, O-4N dodtun Aydioricle CAJa0H) nding phinet Hlien ar thdicatos » ; Let of OTN NadH= 0-005349 gy, AN Hye Way *% O Used on Aeidifier bo tank achlobydun ® Jt uy used as expectorenrt , ihc & Arbre ald fing Ogirt . ® bb iy used to mantel Atak met of Am UIT olin orelerd . tie uatne ok Ocid pH Py the PAGE 4 Ae Dil: Adoric © Metiutar Formula 9 HO * Synonym — § piait of dole , Muriatle acid . Method of Prup aration — St ws prrpareel by Mactirg Arudphuic acid CHiS04) with Aodium chlortol. CNacl) amd parsing Hu Athersted Hct thrsugl, water Nach + HiSdy——» Htt t Nah soy frobeticy © Jk da nealy colerli, lear anal fuming bins a ® 4t bodden ey tA p tang ont Odour. © 4b us deluble whl, water ancl alested. @ §t dy a atiory acid anol Aitticles medals, formdng bbe Arydac chlorides With te welstion A gay. Urea O Jt us weed as acidifiers. treat ype chlor hyolrin. @ Jt Ws used as Phumacentivl aida. fAae> —> Gdet prsberticn of Antacids * O Jt should not Come Ayptenic atkalors @ Jt Ahould rot be a focatiue ob caun com pation. @ 4k Ahewld exect wh effet Anbidly and orn a dong periad of time. ® 4 Ahowtel Aer bupfer dn the PH Page ef 4-6. @ SE Ahoukd not Tntefor with food absohon. — Some Comma Antacioly © *Sodiwm Bicarbonate * » Moltewlar Weight > B4 g * Moleentar formula Natcog e Sg qehyms Sodium Hyoltog en Crbenate, Baleing Soca, Mia Soca. . Prrparsion > © gt ds Poépand by pesing COs gas threugl, & AglHon of Soolimm Aydhoni dc 2 Nao + COr —> Na, Coz + HO Na, Cog +H,0 + CO, —> 2 NaH, ® Solvay Proce CAmmonix Soca Proce) > dy Hus Arnioria And Corben Moxide Atect to form Ammonium biarbo- hate which futher uneletgo cecrmposiion ty form Sodisim Ri carbone. NMg + COr + Hi0 —> NHyHOds NHyhWg + Nach —> Noho, +NHuat PAGE + + Phupi cat frcbetioo @ 9b econ ay white CAypbablint OL Arnot hous poweler hauning ao Aaline tak. i @ gta Aglken vis alholim Pr hebmu . @® Sts facely Acluble wit, wake but practically Insoluble Un alcohol. @ Jt wu stable avy dn by form » Assay —> Weigl, accuntel about 0-6 gu oY Aodittn Garbo - hate anol olidagloe Py SO bab of water Ql tits ok ith O-S mt] He acid, (Snsicator: Cromobh erat blue TS). * bey Osired 2d dyrtacrd to heutAalise acid. @ WUesl fr PAapawtion & butter Aclationa C Na Hey t HiCo2) @ Wal as Necol applicant for burma Tareetes bite ete. @ Alwntniun Hyploride Cel: + Chemical formula At COW) 2 . Sima wpm Muni nian Myploxide Powder, Aluminium Lypkabel povoder. nium Chloride ud bAtatecl votth Ammenia of Sodiun Gibo- pot» & white qual woud baecipitate of alumi widen Aolaxide usa Oblulved. A dl, + 3 NHYOH —> AC OOH); + 3 NHace PAGES _CATHARTICS. — Chat o mou be defines an thor drugs which aw Urea bo bAing about aly eeotiOn i-e Crap tying of a stone, > They ore wed bo To Adie pom aude Combibation ( passing Lys then, 3% bowl mouemeat Um a weed). » To clay bowels frees Atom ach, befou ets A —> Coubpation or otha Arctal obts ordew be Geum clur bo Weak dntitie, Intatinl Shorr | Chased weedy fh Aigestioe trret) , dinjung , dase Y A* Arays Anal oltel. Forms of Gthabes # © Pargativa > the arr A ig Lrtich, Ore basically vusrel to Ammer foveal mrateiel. thuse ae mul voting Cothanti ca ttiel, Cha utaed bo bret coalibation. ~ Loatives ar Chamifiesl dato fier Cates ovteo % © Siren Laxedives Lhese Oct on the datos Hel tact bo uUnwnr dts hater actin ty egy phenol pHaldn ; Castor ot , aloemua ett. (o) Loxah yw —> PAGE > 10 @® Bute forming Laradiver—> Hy Uacuare biatle Saka bel Com- tak anal bowel hivenenld- us, Jaobget » cello ete. @ Ludbrdcauts Lonativer > these lAuga Crrineral gil & vepte- ble eth) ulubai cate He dru thet black » dof ken tHe Jar- Cal waboccl ack veblicale He pamege ap pee - eg, Li gpl parehfin ; Cy Uy contre ett. @M Saltye Laxative = there Juma the Odmelt Leash o Utubre totich Une He bowel pavement. eg-, Sodium PotaMiton Tartarate, Hag neni Sulphate ek. Seme Commen Codh atics 0) Mag nteaiun Sup hake » Melseutar Formula My S04. F HO + Synowyms—+ Epdom Salt wtruparstion > 9+ da papaud ba Action diddeal Sanlph- ric aetd sit Magn of ave Corbovrete or Mag heise Oxide. H, Soy + My COg —> M3Soy +0 + Coet HiSoy + MgO —> Hg Sou + H,0 - bitter taste @ Jb ws rAolble th wate aA sparingly / slighty Selle es l C U PAGE >1) ° Proberkies O Jt ocours ao Vey Hine dclourlen » Cram bo JAryish wohih Coleurasl ok eutty dn Kinte . D Jt us dusvlable ua water but Aebble th panic sebuah. > Uses —s Jt in used a filler Phy phar aceuhiials aoa ako uued a Auapeodirg ght. O) kal? : » Moketers Formula MrO2.2S10..2H,0 . SApno hwy Cling Coby. + Paparsdion—+> Jt vis popard thm Ave db bined, Sebati anol Har fanfe cual Hes Waahed wtf Water Aol Huy Powdlerd . ° Pasbertion © Its colour meq be tinged gay, Yellow browr , blue Ho Act duc to fmpauiter. @ Gt us doapy to touch . . hea > @ thy ar aduobet, ati- lonhoeal why qr en Crate @ Tha OAK comp Low uv, the SYrmpathomah'e tAcatinet “ aliarM,oen, to Cook ritatal Prteatnad mucosa. PAGE > 13 ANTIMICROBINL AGENTS —> An audfmiuebial Ja a Aubsbonce Hak Kill 01 Lnhibets the growth % bicew- Ctyariim Auch ao bacterin, Hugi —> Thue an moing work as Witabicdal (lo Kill) oO Wide biostatic ¢ paumut th the growth 4 hiobex) ty Weturr . + Thue ar uued un the pépation Y mouthwashes, Avabs , dtoctrant , Lyrosk & neral ApAsy etc. or Aubstances used ef — ® Comiddes—> Thue ww Hee Awleatewers lekich [eu mac ~ Orgaricim Anat uisel for both Muir and hey - Living sam] aced - «These an alos Lumed oA hactericide » fungi cicle , Ld ma cha ek - OG Backaiostotic — These an He Aubstemed Which bAina- ANT TIE Ca if ba dani biting the growth of backellas” They lo het Ki bak stop backed 9 rout, Page> 14 + Propetica— Qt Ws Car, colomten Liynisl Aasing brite Qudic Aayte whit us Actible Th water, . Aanay —> Tit Aste Jo mt a Admble why O-IN Pobartium, bom Agtion fy the pauencr & SN HiSdy Wnsil a7 daft binke celeur Uy obbefuesdl. Edel, nh MH OIN KMydy = 0: OO! Fo) gw of MH. 0, » Urey ® Jt us wed ay Alia in| ccbenct 1 Ambi-trechwe arvol oles chact @ 44 us also ued for bleaching ard tooth whi bering , @ Chlorinoted Lime » Nol For ta—> Caod,. HO ° Saya My Clu un, Arypr chhonri te ans boca! : Prebaraki om — Jt ds papared ba taut oxtice vHH, CALoine i ak ae gue Go Cou), + Clr —> Caoc, + HO . Pio f exticn — © gt is nee Or Givy powder Whith Alors ooltu 4 @ 94 vin partially soluble th water & alcohol. » Akes —> O 9t vis seal ay thiridcbial bnalvdy for bacteri clolat 0k EM. G gt vs Wocelly used un alip theia , Scatt tou ete. PAGE 16