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Karch's Focus on Pharmacology 8th Ed. Chapter 9 Exam Questions with Answers, Exams of Pharmacology

Karch's Focus on Pharmacology 8th Ed. Chapter 9 Exam Questions with Answers

Typology: Exams

2024/2025

Available from 06/09/2025

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Karch's Focus on
Pharmacology 8th Ed. |
Chapter 9 Exam Questions
with Answers
Aminoglycosides are contraindicated for all of the following clients EXCEPT: - Correct Answers: Clients
with drug-resistant TB.
A patient with TB is admitted to a health care facility. The nurse is required to administer an
antitubercular drug through the parenteral route to this patient. Which of the following precautions
should the nurse take when administering frequent parenteral injections? - Correct Answers: Rotate
injection sites for frequent parenteral injections.
A client is administered a third-generation cephalosporin. The broad-spectrum agents like
cephalosporins are most effective in treating which type of microorganism? - Correct Answers: Gram-
negative
What organ system is responsible for the excretion of cefotaxime sodium from the body? - Correct
Answers: Renal
A client is allergic to penicillin and has been diagnosed with a genitourinary infection caused by
Chlamydia trachomatis. Which medication will most likely be administered? - Correct Answers:
Erythromycin
Rationale:
A client who is diagnosed with a genitourinary infection that is caused by trachomatis and who is allergic
to penicillin should be administered erythromycin since there is no known cross-reaction. Acamprosate
calcium is administered as a substance abuse deterrent, not in place of penicillin. Atazanavir is an
antiviral agent that is used to treat HIV infection, not Chlamydia trachomatis. Flumazenil is a
benzodiazepine antagonist and not used for Chlamydia trachomatis.
The health care provider considers prescribing an oral tetracycline for a client suspected of having a
urinary tract infection. What action needs to be completed before the medication can be prescribed? -
Correct Answers: The health care provider should order culture and susceptibility studies.
Rationale:
Culture and susceptibility studies are needed before tetracycline therapy is started, because many
strains of organisms are either drug resistant or vary greatly in drug susceptibility. Teaching the client
about proper storage and adverse effects, including photosensitivity, are appropriate after the
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Karch's Focus on

Pharmacology 8th Ed. |

Chapter 9 Exam Questions

with Answers

Aminoglycosides are contraindicated for all of the following clients EXCEPT: - Correct Answers: Clients with drug-resistant TB. A patient with TB is admitted to a health care facility. The nurse is required to administer an antitubercular drug through the parenteral route to this patient. Which of the following precautions should the nurse take when administering frequent parenteral injections? - Correct Answers: Rotate injection sites for frequent parenteral injections. A client is administered a third-generation cephalosporin. The broad-spectrum agents like cephalosporins are most effective in treating which type of microorganism? - Correct Answers: Gram- negative What organ system is responsible for the excretion of cefotaxime sodium from the body? - Correct Answers: Renal A client is allergic to penicillin and has been diagnosed with a genitourinary infection caused by Chlamydia trachomatis. Which medication will most likely be administered? - Correct Answers: Erythromycin Rationale: A client who is diagnosed with a genitourinary infection that is caused by trachomatis and who is allergic to penicillin should be administered erythromycin since there is no known cross-reaction. Acamprosate calcium is administered as a substance abuse deterrent, not in place of penicillin. Atazanavir is an antiviral agent that is used to treat HIV infection, not Chlamydia trachomatis. Flumazenil is a benzodiazepine antagonist and not used for Chlamydia trachomatis. The health care provider considers prescribing an oral tetracycline for a client suspected of having a urinary tract infection. What action needs to be completed before the medication can be prescribed? - Correct Answers: The health care provider should order culture and susceptibility studies. Rationale: Culture and susceptibility studies are needed before tetracycline therapy is started, because many strains of organisms are either drug resistant or vary greatly in drug susceptibility. Teaching the client about proper storage and adverse effects, including photosensitivity, are appropriate after the

medication is ordered. There is no cross-allergenicity with penicillin, so prescribing a tetracycline does not require assessment penicillin hypersensitivity. A client has been prescribed INH for the treatment of tuberculosis. The nurse teaches the client about dietary restrictions while taking this medication. What is the most important instruction? - Correct Answers: "Do not drink beer or red wine while taking this medication because a serious adverse reaction can occur." A nurse is providing education to a client who is taking INH. The nurse is teaching the client to avoid which foods? - Correct Answers: Cheese, dairy products, and bananas Michael, 25 years old, has had mitral valve regurgitation since age four, after having rheumatic fever. Michael is planning to go to his dentist to have his teeth cleaned. Because of Michael's history he will need to take antibiotics in conjunction with this procedure to prevent bacteremia. Which class of antibiotics will Michael most likely receive if he has no allergies? - Correct Answers: Penicillin A nurse is speaking to a 62-year-old female client who has been started on sulfisoxazole, a sulfonamide antibiotic. The nurse should teach this client to contact the health care provider if the client experiences what adverse effect associated with the drug? - Correct Answers: skin rash or itching Aminoglycosides must be used cautiously in children as in adults. Dosage must be accurately calculated according to which factors? - Correct Answers: Weight and renal function A male client is admitted to the unit with Pseudomonas aeruginosa sepsis. The health care provider orders aminoglycoside to be given concomitantly with penicillin intravenously. How would the nurse administer these drugs? - Correct Answers: By administering the drug in separate IV bags A nurse is caring for an adult client diagnosed with bacterial sinusitis. The nurse has cautioned the client against taking prescribed oral erythromycin together with antacids. What is the basis of this instruction?

  • Correct Answers: Antacids decrease the absorption of the drug. What event triggers the development of a superinfection? - Correct Answers: proliferation of antibiotic- resistant microorganisms The nurse caring for a client diagnosed with Mycoplasma pneumonia should prepare medication information on what medication? - Correct Answers: doxycycline A client prescribed rifaximin for diarrhea has developed frank bleeding in the stool. What intervention should the nurse anticipate being implemented to best ensure client safety? - Correct Answers: changing to a different antibiotic A 10-year-old client is diagnosed with acute otitis media. What does the nurse anticipate the health care provider will prescribe? - Correct Answers: Amoxicillin A client is diagnosed with an infection attributable to the gram-negative microorganism Pseudomonas. Which anti-infective agent is most reliable in treating this microorganism? - Correct Answers: Aminoglycoside

A male client is placed on an IV regimen of aztreonam. The nurse would expect the health care provider to order which laboratory test? - Correct Answers: Liver function A client is diagnosed with VRE, and the health care provider orders chloramphenicol. The nurse should monitor the client for the development of which side effect? - Correct Answers: Blood dyscrasias A client with an upper respiratory infection has been prescribed macrolides. Which changes during an ongoing assessment would lead the nurse to notify the health care provider? Select all that apply. - Correct Answers: drop in blood pressure increase in respiratory rate sudden increase in temperature Clients taking isoniazid (INH) can experience a variety of adverse reactions but should be monitored carefully for which of the following that indicate toxicity? Select all that apply. - Correct Answers: Peripheral neuropathy Jaundice