Karch's Focus on
Pharmacology 8th Ed. |
Chapter 2 Exam Questions
with Answers
Chemotherapeutic agents are drugs that - Correct Answers: interfere with foreign cell functioning, such
as invading microorganisms or neoplasms.
Receptor sites - Correct Answers: are protein areas on cell membranes that react with specific
chemicals.
Selective toxicity is - Correct Answers: the ability of a drug to attack only those systems found in foreign
or abnormal cells.
When trying to determine why the desired therapeutic effect is not being seen with an oral drug, the
nurse should consider - Correct Answers: food altering the makeup of gastric juices.
Much of the biotransformation that occurs when a drug is taken occurs as part of - Correct Answers: the
first-pass effect through the liver.
The half-life of a drug - Correct Answers: is determined by a balance of all pharmacokinetic processes.
J.B. has Parkinson disease that has been controlled for several years with levodopa. After he begins a
health food regimen with lots of vitamin B6, his tremors return, and he develops a rapid heart rate,
hypertension, and anxiety. The nurse investigating the problem discovers that vitamin B6 can speed the
conversion of levodopa to dopamine in the periphery, leading to these problems. The nurse would
consider this problem - Correct Answers: a drug-drug interaction.
When reviewing a drug to be given, the nurse notes that the drug is excreted in the urine. What points
should be included in the nurse's assessment of the patient? - Correct Answers: c. The patient's renal
function tests
d. The patient's fluid intake
