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Impact of Preeclampsia on Birth Outcomes: Risks of Poor and Excessive Fetal Growth, Slides of Public Health

The association between preeclampsia and poor fetal growth (sga, lbw) as well as excessive fetal growth (lga, hbw). Figures and studies that illustrate the impact of preeclampsia on birth weight based on gestational age. The document also challenges the current theory that reduced uteroplacental perfusion is the unique pathophysiologic process in preeclampsia.

Typology: Slides

2012/2013

Uploaded on 11/21/2013

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IMPACT OF PREECLAMPSIA
ON BIRTH OUTCOMES
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Download Impact of Preeclampsia on Birth Outcomes: Risks of Poor and Excessive Fetal Growth and more Slides Public Health in PDF only on Docsity!

IMPACT OF PREECLAMPSIA

ON BIRTH OUTCOMES

Preeclampsia

A syndrome characterized mainly by hypertensionand proteinuria after 20 weeks of gestation.

A leading cause of maternal and perinatal morbidityand mortality worldwide.

Unknown etiology and pathogenesis.

No treatment (except early delivery:

preterm birth).

No prevention.

Fig 1. PIH and Low Birth Weight(N=97,

Alberta, Canada)

5,

10,

26

0 50 40 30 20 10

Non-PIH

GH

PE

LBW(%)

Fig 2. PIH and Preterm birth(N=97,

Alberta, Canada)

Non-PIH

GH
PE

Preterm Birth (%)

IMPACT OF PREECLAMPSIA ON BIRTH OUTCOMES

Preeclampsia is associated with an increased riskof poor fetal growth (SGA, LBW)

Preeclampsia is associated with an excessive fetalgrowth (LGA, HBW)

Fig 4. Preeclampsia & High Birth Weight (>4000 g)(N=14,461, Suzhou, China, 1989-1990)

3,

3,

4,

3,

8 6 4 2 0 10

Non-PIH

GH

PE

Severe PE

High birth weight (%)

Fig 6. PIH and Large for Gestational Age(N=97,

Alberta, Canada)

2,

4,

4,

8 6 4 2 0 10

Non-PIH

GH

PE

LGA (%)

Preeclampsia and fetal growth(Xiong et al, Am J Obstet Gynecol 1999;180:207-13)(Xiong et al, Am J Obstet Gynecol 2000;183:148-55)

Preeclamptic group

SGA10%

AGA80%

LGA10%

Normotensive group

SGA
AGA90%
LGA

Fig. 7 Effect of PIH on birth weight by gestational age

(Xiong et al, American Journal of Epidemiology, 2002;155:203-9)

0

6000 5000 4000 3000 2000 1000

B irth w e ight (gra m s )

=<

33

34

35

36

37

38

39

40

41

=>

Gestational weeks

Normotensive status

Gestational hypertension

Preeclampsia

IMPACT OF PREECLAMPSIA ON BIRTH OUTCOMES

Preeclampsia is associated with an increased risk of poorfetal growth (SGA, LBW)

Preeclampsia is associated with an excessive fetal growth(LGA, HBW)

Effect of preeclampsia and gestational hypertension onbirth weight is a function of gestational age:

Effect of decreased birth weight is found mostly amongpreterm births. (38.8% preeclamptic women)

Most babies born to mothers with preeclampsia at termactually have normal birth weight for expectedgestational age. (61.2% preeclamptic women)