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biomolecules lipids structure and properties, Study notes of Biochemistry

biomolecules lipids structure and properties

Typology: Study notes

2023/2024

Available from 10/16/2023

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BIOMOLECULES
LIPIDS
Lipids Definition
“Lipids are organic compounds that contain hydrogen, carbon, and
oxygen atoms, which form the framework for the structure and
function of living cells.”
Lipids
These organic compounds are nonpolar molecules, which are soluble only in
nonpolar solvents and insoluble in water because water is a polar molecule. In the
human body, these molecules can be synthesized in the liver and are found in oil,
butter, whole milk, cheese, fried foods and also in some red meats.
Let us have a detailed look at the lipid structure, properties, types and classification
of lipids.
Properties of Lipids
Lipids are a family of organic compounds, composed of fats and oils. These
molecules yield high energy and are responsible for different functions within the
human body. Listed below are some important characteristics of Lipids.
1. Lipids are oily or greasy nonpolar molecules, stored in the adipose tissue of
the body.
2. Lipids are a heterogeneous group of compounds, mainly composed of
hydrocarbon chains.
3. Lipids are energy-rich organic molecules, which provide energy for different
life processes.
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BIOMOLECULES

LIPIDS

Lipids Definition

“Lipids are organic compounds that contain hydrogen, carbon, and oxygen atoms, which form the framework for the structure and function of living cells.”

Lipids

These organic compounds are nonpolar molecules, which are soluble only in nonpolar solvents and insoluble in water because water is a polar molecule. In the human body, these molecules can be synthesized in the liver and are found in oil, butter, whole milk, cheese, fried foods and also in some red meats. Let us have a detailed look at the lipid structure, properties, types and classification of lipids.

Properties of Lipids

Lipids are a family of organic compounds, composed of fats and oils. These molecules yield high energy and are responsible for different functions within the human body. Listed below are some important characteristics of Lipids.

  1. Lipids are oily or greasy nonpolar molecules, stored in the adipose tissue of the body.
  2. Lipids are a heterogeneous group of compounds, mainly composed of hydrocarbon chains.
  3. Lipids are energy-rich organic molecules, which provide energy for different life processes.
  1. Lipids are a class of compounds characterised by their solubility in nonpolar solvents and insolubility in water.
  2. Lipids are significant in biological systems as they form a mechanical barrier dividing a cell from the external environment known as the cell membrane. Lipid Structure Lipids are the polymers of fatty acids that contain a long, non-polar hydrocarbon chain with a small polar region containing oxygen. The lipid structure is explained in the diagram below: Classification of Lipids Lipids can be classified into two main classes:  Nonsaponifiable lipids  Saponifiable lipids Nonsaponifiable Lipids A nonsaponifiable lipid cannot be disintegrated into smaller molecules through hydrolysis. Nonsaponifiable lipids include cholesterol, prostaglandins, etc Saponifiable Lipids A saponifiable lipid comprises one or more ester groups, enabling it to undergo hydrolysis in the presence of a base, acid, or enzymes, including waxes, triglycerides, sphingolipids and phospholipids. Further, these categories can be divided into non-polar and polar lipids. Nonpolar lipids, namely triglycerides, are utilized as fuel and to store energy. Polar lipids, that could form a barrier with an external water environment, are utilized in membranes. Polar lipids comprise sphingolipids and glycerophospholipids.

Some of the different types of lipids are described below in detail. Fatty Acids Fatty acids are carboxylic acids (or organic acid), usually with long aliphatic tails (long chains), either unsaturated or saturated.  Saturated fatty acids Lack of carbon-carbon double bonds indicate that the fatty acid is saturated. The saturated fatty acids have higher melting points compared to unsaturated acids of the corresponding size due to their ability to pack their molecules together thus leading to a straight rod-like shape.  Unsaturated fatty acids Unsaturated fatty acid is indicated when a fatty acid has more than one double bond. “Often, naturally occurring fatty acids possesses an even number of carbon atoms and are unbranched.” On the other hand, unsaturated fatty acids contain a cis-double bond(s) which create a structural kink that disables them to group their molecules in straight rod-like shape. Role of Fats Fats play several major roles in our body. Some of the important roles of fats are mentioned below:  Fats in the correct amounts are necessary for the proper functioning of our body.  Many fat-soluble vitamins need to be associated with fats in order to be effectively absorbed by the body.  They also provide insulation to the body.  They are an efficient way to store energy for longer periods. Examples of Lipids

There are different types of lipids. Some examples of lipids include butter, ghee, vegetable oil, cheese, cholesterol and other steroids, waxes, phospholipids, and fat-soluble vitamins. All these compounds have similar features, i.e. insoluble in water and soluble in organic solvents, etc. Waxes Waxes are “esters” (an organic compound made by replacing the hydrogen with acid by an alkyl or another organic group) formed from long-alcohols and long-chain carboxylic acids. Waxes are found almost everywhere. The fruits and leaves of many plants possess waxy coatings, that can safeguard them from small predators and dehydration. Fur of a few animals and the feathers of birds possess the same coatings serving as water repellants. Carnauba wax is known for its water resistance and toughness (significant for car wax). Phospholipids Membranes are primarily composed of phospholipids that are Phosphoacylglycerols. Triacylglycerols and phosphoacylglycerols are the same, but, the terminal OH group of the phosphoacylglycerol is esterified with phosphoric acid in place of fatty acid which results in the formation of phosphatidic acid. The name phospholipid is derived from the fact that phosphoacylglycerols are lipids containing a phosphate group. Steroids