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Protein and Mineral Metabolism: A Comprehensive Study Guide, Cheat Sheet of Biochemistry

Panjab UniversityBiochemistry

BIOCHEMISTRY Important Topics And Questions

Typology: Cheat Sheet

2020/2021

Uploaded on 02/08/2023

Arshdeep_Nain
Arshdeep_Nain 🇮🇳

6 documents

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Protein Metabolism
Describe the mechanism of transportation of ammonia.
Describe the urea cycle and its regulation.
Give the biochemical basis of ammonia toxicity
Outline important products synthesized from tyrosine
What is the difference between CPS1 and CPS 2?
Glutamate plays a central role in amino acid metabolism.
Tryptophan deficiency causes pellagra like symptoms.
Transport Disorders of amino acid metab
Important products synthesised from tryptophan
Urea cycle
Nh3 transport in blood requires a carrier
Argininosuccinase
CPS 2
7 alpha hydroxylase
Imp compounds synthesized from methionine and cystine
High levels of homocysteine are atherogenic
How does ammonia detoxification in brain differ from that in liver
Catabolism and specialized products synthesized from methionine
Synthesis of nad+ and nadp+ from tryptophan
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Protein Metabolism

Describe the mechanism of transportation of ammonia. Describe the urea cycle and its regulation. Give the biochemical basis of ammonia toxicity Outline important products synthesized from tyrosine What is the difference between CPS1 and CPS 2? Glutamate plays a central role in amino acid metabolism. Tryptophan deficiency causes pellagra like symptoms. Transport Disorders of amino acid metab Important products synthesised from tryptophan Urea cycle Nh3 transport in blood requires a carrier Argininosuccinase CPS 2 7 alpha hydroxylase Imp compounds synthesized from methionine and cystine High levels of homocysteine are atherogenic How does ammonia detoxification in brain differ from that in liver Catabolism and specialized products synthesized from methionine Synthesis of nad+ and nadp+ from tryptophan

Protein digestion Glutamate acts as collector of nitrogen from alanine Metabolism of methionine and disorders Maple syrup urine disease Specialised products of glycine and tyrosine Alkaptonuria Phenylketonuria may result due to deficiency of dihydrobiopterin reductase Transport of ammonia from muscle to liver Transport disorders Xanthurinic acid excretion Test FIGLU excretion Test Transmethylation reactions Synthesis of creatine Diseass detoxification of ammonia and hyperammonemias Maple Syrup Urine Disease Homocystinuria Alkaptonuria Hartnup's disease

Mineral Metabolism

Selenium decreases Vit E requirement. Hyperkalemia Wilson disease Wilson's disease Wilsons disease Metabolic disorders of Iron Metabolism Regulation of Calcium & Phosphorus metabolism Role of copper & iron in diseases and health Biochemical role of copper in human body Zinc can be used for treatment of Wilsons disease Iron and copper metabolism Short note on Anemia’s Iron absorption and storage Transport and storage of iron Mucosal Block Theory Absorption Transport Storage and Deficiency Disorders of Iron Mucosal Block Theory Iodine metab Actions of Mg Zn P and Se Cu deficiency can lead to anemia Calcium in cells is toxic

Vitamins

Vitamin C deficiency causes bleeding gums. Vitamin A is toxic in excess Vitamin D is considered as a hormone. Calcitriol Blochomical role of Vilamin B12 in the body Rhodopsin cycle Antioxidant prperty of vitamin c and e Folate Trap Vitamin C in maturation of collagen Vitamin D is also called as steroid hormone Vitamin C deficiency can lead to hemorrhagic tendencies. Antioxidant vitamins Vit D deficiency disorders Vit B12 def causes functional folate deficiency Niacin therapeutic uses Syn and functions of vitamin D Pernicious Anemia Vitamins involved in hematopoiesis

Renal rickets Biochem actions of vitamin C Vitamin C cant be synthesized in humans SN on Vit A and Vit E