Anti histaminic agents
Introduction to histamine
Histamine definition
Histamine is a biologically active molecule released by immune
cells that triggers allergic reactions, inflammation, and
regulates various physiological processes, often by binding to
specific receptors on nearby cells.
It is involved in: -
1, local immune responses
2, allergies
3, regulating physiological function in the gut
4, as a neurotransmitter in the brain ( hypothalamus ) .”
• It is present mostly in mast cells ( skin, lungs, GIT mucosa )
• It is also present in non mast cells like ( brain )
