AIDS - Applied Microbiology - Lecture Slides, Slides of Microbiology

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Recent Developments in AIDS

Diagnosis & Treatment

Test Your Hiv/aids iq

• Q:HIV/AIDS is considered a cancerous disease.

TRUE

OR

FALSE

Test Your Hiv/aids iq

• Q: Nearly 33 million in the U.S. are living with HIV.

TRUE

OR

FALSE

Test Your Hiv/aids iq

• Q: HIV is believed to have originated from insects in Brazil.

TRUE

OR

FALSE

Overview

• Introduction to HIV/AIDS
• Transmission of HIV/AIDS
• Diagnosis of HIV/AIDS
• Treatment of HIV/AIDS
• Conclusion

Introduction to AIDS

Public Outbreak of AIDS

• First case in 1981
• Number of young gay men
• First seen in New York and Los Angeles
• 59 million people worldwide

HIV Infection Cycle

• 2 phases: Extracellular & Intracellular
• Virus targets CD4 Receptor, conformational change occurs
• CCR5 Co-Receptor of T-helper cells further binds the virus
• Fusion occurs

Attack on the Immune System

• Immune system fights against virus
• HIV kills off helper T-cells
• Weakens immune system
• Host then becomes vulnerable to secondary infections
• Opportunistic infections

tuberculosis, toxoplasmosis of brain, lymphoma

Infectious phases

1. Viral Transmission
2. Acute HIV infection
3. Seroconversion
4. Clinical Latent Period
5. Early Symptomatic HIV Infection
6. AIDS
7. Advanced HIV infection

HIV distribution by sexual classes

HIV distribution by Ethnicities

Life expectancy with HIV?

• Life expectancy varies
• Better treatment, other factors suppressing virus = longer life
• No permanent cure due to adaptive & reproductive features of HIV

Transmission of HIV/AIDS